The comparison of dietary intake of macronutrients in polycystic ovary syndrome with and without metabolic syndrome

Authors

  • Anoshirvan Kazemnejad Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Azadeh Mottaghi Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.
  • Maryam Movahedinejad Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Narges Zaeemzadeh Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Neda Mohamadzadeh Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Saeideh Ziaei Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Shahideh Jahanian Sadatmahalleh Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Abstract:

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women. The prevalence of PCOS among Iranian women is 14.6% based on the Rotterdam definition. PCOS can increase the risk of chronic metabolic complications. Metabolic syndrome (MetS) is one of the most important of them. Insulin resistance is fundamental in PCOS and MetS pathophysiology. MetS is a collection of chronic metabolic derangements, which promotes the risk of serious diseases such as cardiovascular disturbances and diabetes. The quality of diet is inversely correlated with obesity, which is one of the consequences of PCOS and it is a risk factor for metabolic syndrome. As the first study, the present study aimed to compare the dietary intake of macronutrients in PCOS women with and without MetS. Methods: In this nested case-control study, the convenience sampling method was used to select participants. The case group included 14 PCOS patients with MetS and the control group included 28 PCOS patients without MetS. The investigated macronutrients included fats (total fat, saturated fatty acids, mono and polyunsaturated fats, trans fatty acids), carbohydrate, protein, and fibers (total and soluble). The dietary intake assessment was carried out by a 168-item semi-quantitative food frequency questionnaire (FFQ). This study was performed on Arash Women's Hospital under support of Tarbiat Modares University, Tehran, Iran, from August 2014 to September 2015. Results: Dietary intake of total fat was significantly higher in PCOS women with MetS than the control group (P<0.001, 146.62±45.17 vs. 59.91±32.79 g/d). Dietary intake of saturated fatty acids (P=0.004, 11.44±11.08 vs. 19.73±6.76 g/d), monounsaturated fats (P<0.001, 14.15±12.66 vs. 26.16±7.76 g/d), polyunsaturated fats (P=0.002, 9.02±9.18 vs. 17.22±6.45 g/d), carbohydrate (P<0.001, 182.34±121.08 vs. 365.64±77.11 g/d), protein (P=0.001, 42.74±42.85 vs. 78.06±24.04 g/d), total fiber (P<0.001, 17.77±15.09 vs. 35.97±22.64 g/d) was significantly lower in PCOS women with MetS than the control group. All results are expressed in terms of grams consumed per day. Conclusion: Our results demonstrated that dietary intake of macronutrients was significantly different in polycystic ovary syndrome patients with and without metabolic syndrome.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

P-223: Comparing Dietary Intake in Women with and without Polycystic Ovary Syndrome

Background: Adequate nutritional status is a critical determinant of the onset and maintenance of normal reproductive function. More than 50% of women with PCOS are obese and central obesity plays a central role in the pathogenesis of PCOS by generating an insulin- resistant state, It has been proposed that recurrent hypoglycaemia due to hyperinsulinaemia could lead to decreased post-prandial s...

full text

Metabolic Syndrome in Patients with Polycystic Ovary Syndrome in Iran

Background The prevalence of metabolic syndrome (MetS) in polycystic ovary syndrome (PCOS) has been studied in different populations, but their results were so controversial regarding Iranian women. These controversial data indicated the need for more investigation of MetS characteristics in PCOS patients in our population. So this study aimed to evaluate the clinical and laboratory characteris...

full text

Relationship between Serum Leptin, Ghrelin and Dietary Macronutrients in Women with Polycystic Ovary Syndrome

Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. It may involve an impairment in physiologic regulation of leptin and ghrelin. There is limited, controversial data on the relation of dietary components with leptin and ghrelin in PCOS, so the current study has been conducted to explore the effects of different macronutrients on serum levels of leptin and gh...

full text

I-30: Prevalence of Metabolic Syndrome in Women with Polycystic Ovary Syndrome

Background: Metabolic syndrome is a disorder which is composed of several metabolic abnormalities: glucose intolerance, dyslipidemia, obesity and hypertension. PCOS which is characterized by menstrual irregularities and hyperandrogenism, is a common endocrinological disorder in female reproductive age. The prevalence of the syndrome is 5-10%. Insulin resistance is a common feature of the PCOS (...

full text

Polycystic ovary syndrome and the metabolic syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in female reproductive age. Insulin resistance (IR) and compensatory hyperinsulinemia seem to be the main pathophysiologies of this syndrome. Therefore, PCOS is at risk for abnormal glucose tolerance, dyslipidemia, central obesity and hypertension. Also, plasminogen activator-inhibitor-1 (PAL-1), hemostatic factor and C-reac...

full text

Polycystic Ovary Syndrome and the Metabolic Syndrome

Diabetologists have long recognized the comorbid diseases of obesity, hypertension, and hyperlipidemia in their type 2 diabetic patients, and the necessity of treating these conditions in order to improve outcomes. Cardiovascular disease (CVD) is the number-one cause of death among patients with diabetes, and its prevention is at the forefront of modern diabetes care. The clustering of insulin ...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 77  issue 9

pages  586- 594

publication date 2019-12

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023