SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION

Authors

  • Ali Ezabadi Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
  • Bahram Pourhasan Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran;
  • Mohammad Mahmudi Hashemi Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
Abstract:

A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride  as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.

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Journal title

volume 7  issue 4

pages  23- 28

publication date 2017-12-16

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