Synthesis of 1,3,5-tri-substituted pyrazoles promoted by P2O5.SiO2

Authors

  • Abbas Ali Jafari Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran.
  • Abdolhamid Bamoniri Department of Organic Chemistry, Faculty of Chemistry, University of Kashan , Kashan, I.R.Iran.
  • BiBi Fatemeh Mirjalili Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran.
  • Fatemeh Abasaltian Department of Chemistry, College of Science, Yazd University, P.O.Box 89195-741, Yazd, I.R.Iran.
Abstract:

Silica supported phosphorus pentoxide (P2O5·SiO2) is an efficient catalyst for synthesis of 1,3,5-substituted pyrazoles via the condensation of 1,3-diketones and hydrazines. Simplicity of procedure, mild condition, being solvent-free, high yields, and easy workup are some advantages of this protocol.

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Journal title

volume 2  issue 2

pages  75- 78

publication date 2012-06-01

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