Synovial fluid inflammatory cytokines and proteins in clinically healthy and arthritic joint of dromedary camels (Camelus dromedarius)

Authors

  • Ali Asghar Chalmeh Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • Khalil Badiei Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • Mehrdad Pourjafar Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • Mohammad Hasan Najizadeh Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • Mojtaba Naghib Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • Saeed Nazifi Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Abstract:

Analyzing the synovial fluid is one of the common methods to diagnose the articular problems to detect the stage and express the prognosis. Such gross, cytological, and biochemical analysis of synovial fluids can aid in the diagnosis of various joint diseases. Objectives: Normal values for synovial fluid in the camels have been described previously; however, there are no reports regarding concentr-ation of acute phase proteins and inflammatory cytokines in camelids synovial fluid. Hence, the present study tried to compare the synovial fluid inflammatory cytokines and acute phase proteins in clinically healthy and arthritic tarsal joints of dromedary camels. Methods: 46 male dromedary camels, 5 to 10 years old, were used in this study. 33 camels did not have any clinical articular abnormalities while 13 camels had gross articular problems such as lameness and swollen tarsal joints. Collecting the synovial fluids was extracted from the healthy and arthritic tarsal joints immediately after slaughter. Then, the concentration of haptoglobin, serum amyloid A, tumor necrosis factor-alpha, and interferon-gamma were measured in samples. Results: Concentration of all measured parameters in arthritic joints were significantly higher than clinically healthy joints (p

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Journal title

volume 8  issue 1

pages  53- 57

publication date 2014-04-01

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