Symptom Evaluation in Pediatric Oncology Outpatient Setting; A Cross-Sectional Study

Authors

  • Arash Rashidian Dr A Rashidian, Department of Global Health and Public Policy, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Ava Mansouri Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Kazem Heidari Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Kheirollah Gholami Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Molouk hajibabaie Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Mona Kargar Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  • Rozita Motaghedi School of pharmacy, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  • Shahla Ansari Department of Hematology and Oncology, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran
Abstract:

Detection and management of cancer-related symptoms is a key component in children’s quality of life. We evaluate symptoms and their severity in Iranian pediatric oncology outpatients using Therapy-Related Symptom Checklist for Children (TRSC-C). This was a cross-sectional study conducted in two outpatient pediatric oncology settings. We included all patients aged between 5-17 years. The validated and reliable Persian translated version of TRSC-C was used to study the symptoms. Overall 1425 symptoms were documented from 162 patients (mean age 8.6 ±3.2, acute lymphoblastic leukemia: 76.5%). In 96.3% of patients at least one symptom was present. Twenty (12.34%) patients experienced at least 15 events. Irritable, loss of appetite, cough, pain and hair loss were the top 5 frequent symptoms. The highest mean severity scores were also belonged to irritable, loss of appetite, and hair loss. We found no significant difference between gender, age group or time of the last chemotherapy with mean total severity scores or total number of symptoms (P>0.05). In conclusion, TRSC-C is an appropriate symptom assessment checklist for our settings and it would give us the ability to track symptoms and designate clinical interventions based on the frequent and severe identified symptoms.

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Journal title

volume 15  issue 2

pages  27- 40

publication date 2019-04-01

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