Successful Treatment of Ethylene Glycol Poisoning with Haemodialysis

[Ethylene glycol poisoning].

Although an uncommon cause of death in Great Britain, ethylene glycol poisoning is potentially serious in that renal and cardiopulmonary failure and central nervous system dysfunction can occur when doses of the order of 100 ml or more are ingested. A case is described in which a child who swallowed approximately 100 ml of ethylene glycol was treated by prolonged peritoneal dialysis. In additio...

Current management of ethylene glycol poisoning.

Ethylene glycol, a common antifreeze, coolant and industrial solvent, is responsible for many instances of accidental and intentional poisoning annually. Following ingestion, ethylene glycol is first hepatically metabolised to glycoaldehyde by alcohol dehydrogenase. Glycoaldehyde is then oxidised to glycolic acid, glyoxylic acid and finally oxalic acid. While ethylene glycol itself causes intox...

Ethylene glycol poisoning and lactate concentrations.

We were interested to read the article by Manini et al. (1), which confirmed previous observations that a severe ethylene glycol poisoning may lead to falsely elevated lactate levels (2). High lactate levels were indeed measured by enzymatic spectrophotometry (Integra analyzer) but excluded by a specific GC analysis. A linear correlation was nicely demonstrated between the serially determined b...

Urine fluorescence in ethylene glycol poisoning.

Lactate gap and ethylene glycol poisoning.

EDITOR: We report a case in which we used the GlideScope to facilitate the successful insertion of nasogastric tube. A 66-yr-old male was scheduled for an elective left-sided hemi-mandibulectomy with radial free flap reconstruction for squamous cell carcinoma of the oral cavity. On assessment, the patient’s airway was Mallampati 2 and mouth opening was three fingerbreadths wide. We induced anae...

Acute ethylene glycol poisoning after intentional ingestion

Background: We describe a case of acute ethylene glycol poisoning following ingestion of antifreeze agent in which serum ethylene glycol and anion gap were serially measured. Patients: A 66-year old man was hospitalized after intentional ingestion of automotive antifreeze. Upon admission, vital signs, mental status, and neurological functions were normal. Initial laboratory tests revealed no se...