Successful Propranolol Treatment of a Large Size Infantile Hemangioma of the Face Causing Recurrent Bleeding and Visual Field Disruption
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Abstract:
A 29 days old Pakistani female infant was presented to our outpatient department with two weeks history of a rapidly progressing large size facial hemangioma involving most of the right cheek and right eyelids. The infant was unable to open the right eye. There was also a small hemangioma on the right second toe. Additionally, three similar lesions were found on the right side of the palate and adjoining buccogingival surfaces. The parents were particularly concerned about the explosive progression of the lesions, recurrent bleeding episodes from ulcerated areas of the cheek lesion and complete occlusion of the right eye. Following four weeks therapy with propranolol in a dose of 2 mg/kg/day, the hemangiomas rapidly regressed, the bleeding episodes ceased and the infant started opening the eye.
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successful propranolol treatment of a large size infantile hemangioma of the face causing recurrent bleeding and visual field disruption
a 29 days old pakistani female infant was presented to our outpatient department with two weeks history of a rapidly progressing large size facial hemangioma involving most of the right cheek and right eyelids. the infant was unable to open the right eye. there was also a small hemangioma on the right second toe. additionally, three similar lesions were found on the right side of the palate and...
full text[Treatment of infantile hemangioma with propranolol].
Infantile hemangiomas are proliferative vascular disorders that occur in the pediatric airway, potentially causing airway narrowing and respiratory stress. It appears in 1 out 10 children, more frequently in girls. Hemangiomas are benign tumours that usually appear on the head or neck but may also occur in deep organs. Until recently, the most common medical therapy used was high-dose systemic ...
full textThe role of propranolol in the treatment of infantile hemangioma.
INTRODUCTION Infantile hemangioma (IH) is one of the most common childhood tumors. There are various medical or surgical therapeutic options, all with suboptimal results. Recently, the successful use of propranolol for involution of IH was described. We report the results of a single-center experience with this therapeutic option. OBJECTIVE To prospectively assess the efficacy and safety of p...
full textPropranolol treatment of infantile hemangioma endothelial cells: A molecular analysis
Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting approximately 5-10% of children to varying degrees. During the first year of life, these tumors are strongly proliferative, reaching an average size ranging from 2 to 20 cm. These lesions subsequently stabilize, undergo a spontaneous slow involution and are fully regressed by 5 to 10 years of age. Systemi...
full textPropranolol treatment of infantile hemangioma: clinical and radiologic evaluations.
BACKGROUND There is no way to predict the size that proliferative infantile hemangiomas (IHs) can reach and to expect the occurrence of complications. Moreover, there are no well-known characteristics that can affect the rate of involution of IHs and to predict its completion. Accordingly, intervention is frequently indicated. Different modalities have been reported for treatment of IHs. The po...
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Journal title
volume 4 issue None
pages 79- 83
publication date 2015-01
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