Strategies of vaccine production against COVID-19: when will an effective vaccine be produced?

[When will the nicotine vaccine be ready?].

Ethical Issues in COVID-19 Vaccine Rollout

From the beginning of the COVID-19 pandemic, researchers aspired to produce an effective vaccine with appropriate efficacy and low side effects to mitigate the pandemic. It seems that vaccination is the only mean to save the world from this pandemic. In this article, we will review the ethical challenges of mass vaccination (focusing on the vaccine distribution and uptake), referring to the mai...

The Predictive Role of Vaccine Literacy and Vaccine Hesitancy on Acceptance of COVID-19 Vaccination

Background: Vaccination is preventive behavior, and vaccine literacy and hesitancy appear to influence vaccination. The aim of this study was to determine the role of vaccine literacy and hesitancy on the acceptance of the COVID-19 vaccine. Materials and Methods: In this cross-sectional study, 2185 residents over 18 years old in urban and rural health centers in three cities of Dashtestan, Dash...

Does BCG vaccine induced trained immunity provide cross-protection against COVID-19?

During the global COVID-19 pandemic, the rate of mortality and morbidity was fairly low in Pakistan compared to western countries. Bacille Calmette-Guerin (BCG) vaccination provides cross-protection for a broad range of related and unrelated pathogens. This protection is attributed to the recognition of broadly cross-reactive Pathogen-Associated Molecular Pattern (PAMPS) like molecules. We inve...

Hydroxychloroquine: A bridge prophylaxis till finding the COVID-19 vaccine

Regarding the importance of COVID-19 pandemic and risks that the infection imposes on healthcare workers, this manuscript discusses the potential usage of Hydroxychloroquine as a prophylactic agent.

Will containment of wild poliovirus in laboratories and inactivated poliovirus vaccine production sites be effective for global certification?

The absolute laboratory containment of any virus cannot be guaranteed, but a wealth of experience indicates that effective containment of wild poliovirus materials for global certification is technically and operationally feasible. Effective containment is based on the principles of minimal wild poliovirus infectious and potentially infectious materials in laboratories; minimal risks of operati...