Spurious Hyperleukocytosis
Authors
Abstract:
Hyperleukocytosis is an oncological emergency but is extremely rare in non-malignant conditions. Nucleated RBCs give rise to spuriously high total leucocyte count and cause clinical dilemma. Thalassemia major patients are known to have leucocytosis even after correction for nucleated RBCs. We report a case of undiagnosed Thalassemia major in a 4 month old infant with total leucocyte count higher than one lakh and referred as a case of leukemia. Nucleated RBCs in peripheral blood points to underlying systemic illness and the investigation for the same will avoid delay in diagnosis.
similar resources
spurious hyperleukocytosis
hyperleukocytosis is an oncological emergency but is extremely rare in non-malignant conditions. nucleated rbcs give rise to spuriously high total leucocyte count and cause clinical dilemma. thalassemia major patients are known to have leucocytosis even after correction for nucleated rbcs. we report a case of undiagnosed thalassemia major in a 4 month old infant with total leucocyte count highe...
full textHypoxemia During Extreme Hyperleukocytosis: How Spurious?
BACKGROUND Spurious hypoxemia has been described in case reports during extreme hyperleukocytosis and has led to recommendations for immediate cooling and analysis of arterial blood gases (ABGs). We sought to determine, in samples processed as recommended, the magnitude of spurious hypoxemia in acute leukemia subjects with hyperleukocytosis. METHODS A retrospective chart review was conducted ...
full textHyperleukocytosis: pseudohyperkalaemia and other biochemical abnormalities in hyperleukocytosis.
A 66-year-old woman, recently diagnosed with T cell prolymphocytic leukaemia (PLL) was admitted for cytotoxic therapy, with a potassium (K) of 5.5 mmol/L on admission as measured on a lithium heparin plasma sample (Beckman DxC800; Beckman Coulter Diagnostics, Fullerton, CA, USA). The sample was analysed within 70 min of collection. The white blood cell count (WBC) was 460=10/L (Sysmex XE5000; S...
full text[Pseudo-hypoglycemia and hyperleukocytosis: a case report].
Mrs B., 39 years old, hospitalized in the department of respiratory medicine for lung cancer, has an undetectable and verified venous blood glucose concentration (measured in central laboratory) less than 0.1 mmol/L. The patient feels no symptom of hypoglycemia. A concomitant capillary determination realised by a bedside glucose reader gives a result of 4.7 mmol/L. This gap is due to glucose co...
full textEpileptic Seizure, Postictal Hemiparesis, and Hyperleukocytosis
Introduction: Acute ischemic stroke (AIS) is a rare event in infancy. Besides vasculopathy, thrombophilia, or cardiac disorders, cancer and chemotherapy are known predisposing factors for AIS. Leukemia can be associated with different abnormal coagulation parameters, but severe bleeding or thrombosis occurs rarely. Clinical Course: We report the case of a 2-year-old boy who was presented to our...
full textTherapeutic apheresis in hyperleukocytosis and hyperviscosity syndrome.
Therapeutic apheresis (TA), as a way of rapidly eliminating harmful or excessive blood components such as plasma proteins (plasma exchange) or cells (leukapheresis and platelet apheresis), has found broad application in a vast array of hematologic disorders. The most common hematologic indications for TA are leukocytosis in acute leukemias and hyperviscosity syndrome secondary to plasma cell dy...
full textMy Resources
Journal title
volume 3 issue 4.2
pages 799- 800
publication date 2015-08-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023