Severe combined immunodeficiency presented with septic arthritis: A case report

Authors

  • Bahrami, Ahmad Department of Asthma Allergy & Immunology, Ali Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran
  • Rezaei, Nima Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Dr. Qarib St, Keshavarz Blvd, Tehran14194, Iran.
  • Smaeelnezhad, Hamideh Department of Asthma Allergy & Immunology, Ali Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran.
  • Vafapour, Maryam Department of Asthma Allergy & Immunology, Ali Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran
Abstract:

Severe combined immunodeficiency is a rare, fatal syndrome of diverse genetic cause in which there is combined absence of T-lymphocyte and B-lymphocyte function (and in many cases also natural killer, or NK lymphocyte function). These defects lead to extreme susceptibility to serious infections. Without intervention, the T and B-cell dysfunction usually results in severe infection and death in children by age 2 years. Here, we report a case of SCID in a 37-day-old male infant was admitted to pediatric intensive care unit (PICU) in our hospital with complain of the right knee swelling.

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volume 4  issue None

pages  0- 0

publication date 2019-11

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