Serologic Evidence of Pertussis Infection in Vaccinated Iranian Children

Authors

  • Abdollah Karimi Department of Pediatric Infectious Diseases, Pediatric Ward, Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Anahita Sanaei Dashti Department of Pediatric Infectious Diseases, Pediatric Ward, Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Farideh Shiva Department of Pediatric Infectious Diseases, Pediatric Ward, Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Hassan Joulaei Vice-Chancellor for Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Mohsen Moghadami Vice-Chancellor for Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Reza Arjmand Department of Pediatrics, Pediatric Ward, Shahrekord University of Medical Sciences, Shahrekord, Iran
  • Taherh Kheirkhah Health Policy Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Zari Gholinejad Department of Pediatric Infectious Diseases, Pediatric Ward, Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:

Background: It seems that the incidence of pertussis-like illnesses is considerably increasing despite the wide coverage of immunization with the whole cell pertussis vaccine. We aimed to investigate the occurrence of pertussis in vaccinated children by measuring anti-pertussis antibodies. Methods: In this cross-sectional study, blood samples were taken from vaccinated children aged 2, 4, 6, 12, 18, and 72 months. Anti-pertussis IgG and IgA were measured by ELISA. P

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Journal title

volume 37  issue 4

pages  260- 265

publication date 2012-12-01

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