Role of Amorphous Calcium Phosphate in Dentistry

Authors

  • Azam Valian Dept. of Operative Dentistry
  • Maryam Moezzizadeh Dept. of Operative Dentistry
Abstract:

  Objective: Amorphous calcium phosphate (ACP) is a reactive solution capable of releasing calcium and phosphate ions, conversion to apatite and remineralization of mineral tooth structure. This study reviews ACP structure, its properties and its applications in dentistry.   Methods: In this review study, keywords including “amorphous calcium phosphate”, “mineralization”, “hydroxyapatite”, “casein phosphopeptide”, “tissue engineering” and “dentistry” were searched in articles published during 1953-2013 in PubMed, Science Direct, Google Scholar, Embase and Medline databases. A total of 134 articles were evaluated.   Results: ACP had high adhesion, adjustable dissociation rate, bone induction and excellent biocompatibility without cell toxicity. ACP alone or in combination with casein phosphopeptide (CPP) is incorporated into toothpastes, chewing gums, mouth rinses, tooth bleaching gels and food products to enhance remineralization and prevent demineralization. Also, it is used as filler in many dental materials namely glass ionomers, composite resins and bonding agents. Implant surface coating with ACP by radio frequency magnetron sputtering improves osseointegration especially at the final stages of healing.   Conclusion: ACP is suitable for tissue regeneration and healing and is a potential remineralizing agent in dentistry.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

role of amorphous calcium phosphate in dentistry

objective: amorphous calcium phosphate (acp) is a reactive solution capable of releasing calcium and phosphate ions, conversion to apatite and remineralization of mineral tooth structure. this study reviews acp structure, its properties and its applications in dentistry.   methods: in this review study, keywords including “amorphous calcium phosphate”, “mineralization”, “hydroxyapatite”, “casei...

full text

Amorphous calcium phosphate and its application in dentistry

Amorphous Calcium Phosphate (ACP) is an essential mineral phase formed in mineralized tissues and the first commercial product as artificial hydroxyapatite. ACP is unique among all forms of calcium phosphates in that it lacks long-range, periodic atomic scale order of crystalline calcium phosphates. The X-ray diffraction pattern is broad and diffuse with a maximum at 25 degree 2 theta, and no o...

full text

Application of Calcium Phosphate Materials in Dentistry

Calcium phosphate materials are similar to bone in composition and in having bioactive and osteoconductive properties. Calcium phosphate materials in different forms, as cements, composites, and coatings, are used in many medical and dental applications. This paper reviews the applications of these materials in dentistry. It presents a brief history, dental applications, and methods for improvi...

full text

Review of casein phosphopeptides-amorphous calcium phosphate.

Casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) is a bioactive agent with a base of milk products, which has been formulated from two parts: casein phosphopeptides (CPP) and amorphous calcium phosphate (ACP). CPP was produced from milk protein casein and has a remarkable ability to stabilize calcium phosphate in solution and to substantially increase the level of calcium phosphate ...

full text

Comparison the effect of casein phosphopeptide amorphous calcium phosphate and fluoride varnish on dentin hypersensitivity reduction

Introduction: Nowadays, several casein components such as casein phosphopeptide amorphous calcium phosphate (CPP-ACP) are vastly considered as a suitable replacement for fluoride component . The aim of this study was to compare the effect of CPP-ACP paste and fluoride varnish on dentin hypersensitivity reduction. Materials & Methods: In this clinical trial study, thirty adult patients betwee...

full text

effect of casein phosphopeptide-amorphous calcium phosphate and acidulated phosphate fluoride gel on erosive enamel wear

background: some studies have shown that casein phosphopeptide-amorphous calcium phosphate (cpp-acp) and acidulated phosphate fluoride (apf) gel can protect teeth against erosion. the aim of this study was to assess whether cpp-acp and fluoride could reduce enamel wear rates under erosive conditions simulating abrasion and acidic diet regimen. materials and methods: enamel specimens consisted o...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 32  issue None

pages  53- 63

publication date 2014-02

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023