Role of Aberrant Alternative Splicing in Cancer
Authors
Abstract:
Alternative splicing can alter genome sequence and as a consequence, many genes change to oncogenes. This event can also affect protein function and diversity. The growing number of study elucidate the pathological influence of impaired alternative splicing events on numerous disease including cancer. Here, we would like to highlight the significant role of alternative splicing in cancer biology and emphasize the necessity for conducting more research into target alternative splicing as a treatment for cancer.
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1 Dipartimento di Biomedicina e Prevenzione, Università di Roma Tor Vergata, Via Montpellier 1, 00133 Roma, Italy 2 Fondazione Santa Lucia, Laboratorio di Neuroembriologia, Via del Fosso di Fiorano 64, 00143 Roma, Italy 3 Faculty of Health and Life Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK 4 Istituto di Genetica Molecolare, Consiglio Nazionale delle Ric...
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1 Inserm U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, 69008 Lyon, France 2 Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal 3 Institució Catalana de Recerca i Estudis Avançats (ICREA) and Centre de Regulacio Genomica, Barcelona, Spain 4 Istituto di Genetica Molecolare-Consiglio Nazionale delle Ricerche, Pav...
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Journal title
volume 9 issue None
pages 1- 4
publication date 2021-06
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