Risk of Acute Blood Potassium Elevation After Succinylcholine Injection

author

  • Mohammad Taghi Saeidi Department of Anesthesia and Animation, Faculty of Medicine, National University of Iran, Tehran, Iran.
Abstract:

SUMMARY  An abnormal increase in serum potassium afte-r administration of suxamethonium is known to occur in the treatment of burns, trauma, teta­nus and neurological disorders. A table shows how long this abnormal reaction lasts approxi­mately in the different categories. A few cases of cardiac arrest following suxamethonium in­jection are described in detail. The pa;thogene­sis of this abnormal efflux of potassium is dis­cussed. Prophylaxis consists of being aware of the contraindications of suxamethonium men­tioned above and of using only nondepolarizing relaxants in such cases. When there is some special indication for suxamethonium adminis­tration the potassium increase can be mini­mized if the patient is. given a small dose -of nondepolarizing relaxants five minutes prior to suxamethonium injection. The treatment of cardiac arrest due to acute hyperkalaemia is briefly mention. Zusammenfassung  Bisher sind die folgend-en Patienten-Katego­ri-en bekannt, die auf eine Injektion von Succi­nylcholi.n mit einem abnormalen Ansteigen des Serumkaliums reagieren: Verbrennungen. Poly­traumatiker, Tetanus, neurologi:sche Leiden. Falle mit akutem Nierenversagen sind vermut­lich nur dann gefahrdet, wenn sie bereits mit einem hohen Kaliuwert zur Narkose Rommen. Eine TabeHe orientiert i.iber die Dauer dieser abnormalen Reaktion. Zu den letzten vier Pati­engruppen wird je ein Fall vorges:tellt, wo es aufgrund eines durch Succinylcholin induzierten Kaliumanstieges zum Kreislaufstill'stand gekom­men ist. Die Pathogenese dieser ungewohn­lichen Kaliumausschtittung wird diskutiert. Die Prnphylaxe besrteht in erster Linie im Wissen um die·se Gefahr und in der ausschliesslichen Anwendung von nicht depolarisierenden Rela­xantien bei gefahrdeten Pa ti en ten. W o doch bei einem solchen Fall eine relative Indikation zur Anwendung von Succinylcholin besteht, kann das Ansteigen des Serumkaliums durch vorherige InjeMion einer kleinen Dosi:s eines nicht depolarisierenden Relaxans gedampft werden. Abschliessend ist die Behandlung eines durch eine akute Hyperkaliamie zustande gekommenen Kreislaugstillstandes erortert. 

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

What Causes the Acute Blood Pressure Elevation After Stroke?

What Causes the Acute Blood Pressure Elevation After Stroke? To the Editor: In an insightful editorial1 to a recently published paper by Mattle et al,2 Lindsberg raises a central question as to why blood pressure increases in the acute phase of stroke. The Cushing reflex is suggested as a possible mechanism because it results in sympathetic nervous system activation; however, this reflex is typ...

full text

What Causes the Acute Blood Pressure Elevation After Stroke ?

What Causes the Acute Blood Pressure Elevation After Stroke? To the Editor: In an insightful editorial1 to a recently published paper by Mattle et al,2 Lindsberg raises a central question as to why blood pressure increases in the acute phase of stroke. The Cushing reflex is suggested as a possible mechanism because it results in sympathetic nervous system activation; however, this reflex is typ...

full text

What Causes the Acute Blood Pressure Elevation After Stroke? * Response:

What Causes the Acute Blood Pressure Elevation After Stroke? To the Editor: In an insightful editorial1 to a recently published paper by Mattle et al,2 Lindsberg raises a central question as to why blood pressure increases in the acute phase of stroke. The Cushing reflex is suggested as a possible mechanism because it results in sympathetic nervous system activation; however, this reflex is typ...

full text

Anectine® (Succinylcholine Chloride Injection, USP)

Therefore, when a healthy appearing infant or child develops cardiac arrest soon after administration of succinylcholine not felt to be due to inadequate ventilation, oxygenation, or anesthetic overdose, immediate treatment for hyperkalemia should be instituted. This should include administration of intravenous calcium, bicarbonate, and glucose with insulin, with hyperventilation. Due to the ab...

full text

Asystole after alfentanil- succinylcholine

To the Editor: Alfentanil is a new narcotic capable of blunting intraoperalive haemodynamic responses while allowing for return of spontaneous ventilation and consciousness after short surgical procedures. We have recently noted reports of severe bradycardia with the use of alfentanil combined with succinylcholine, t,2 We also present such a case. A 76-year-old 45 kg woman was scheduled for rem...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 2  issue 1

pages  63- 67

publication date 1973-10

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023