Production and standardization of polyvalent Clostridium perfringens vaccine in Iran

Authors

  • H. Darakhshan
  • M. Ardehali
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Production and standardization of polyvalent Clostridium perfringens vaccine in Iran.

In this presentation an account of the large-scale production and the standardization of polyvalent Clostridium perfringens vaccine in Iran is described. Over 20 million doses of this vaccine are produced and utilized in Iran every year. Certain modifications have been made to the culture media used in our laboratory for the production of this vaccine in order to bring down its cost. The prepar...

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Regulation of Toxin Production in Clostridium perfringens

The Gram-positive anaerobic bacterium Clostridium perfringens is widely distributed in nature, especially in soil and the gastrointestinal tracts of humans and animals. C. perfringens causes gas gangrene and food poisoning, and it produces extracellular enzymes and toxins that are thought to act synergistically and contribute to its pathogenesis. A complicated regulatory network of toxin genes ...

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Journal title

volume 29  issue 1

pages  45- 54

publication date 1977-02-01

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