Precision medicine, technologies, and molecular diagnostics

Authors

  • Eslami, Maryam Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran-Dept.of Genetics, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  • Hariri, Kimia Pharmaceutical Sciences Dept., University of Southern California School of pharmacy, Los Angeles, California, USA
  • Mojahed Yazdi, Helia Pharmacology and Drug Development, Tufts University School of Medicine, Boston, Massachusetts, USA
  • Rouhollah , Fatemeh Cell and Molecular Biology Dept., Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Abstract:

Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible that patients respond differently to a single treatment. Personalized medicine is a new field of medicine aims to tailor medical treatments to the individual characteristics of patients. In this review, in addition to genomics and personalized medicine, we touch upon common techniques in this field and the future of personalized medicine. With this development, people can get more information about the possibility of contracting diseases like cancer and early-stage treatments as well as personalized therapies based on their genetic characteristics. Technologies, such as mutation detection in the genome, microarrays or microchips, and next-generation sequencing of the human genome, have not only made molecular detection better and easier but also facilitated the integration of molecular detection with targeted drug delivery for the development of novel personalized treatment.

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Journal title

volume 24  issue 2

pages  221- 229

publication date 2022-04

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