Post-operative radiotherapy of keloids. A 10-years experience of kilovoltage irradiation

Authors

  • A. Pontoriero Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy
  • A. Potami A.O.U. “G. Martino” Operative Unit of Radiation Oncology, Messina, Italy
  • C. De Renzis Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy
  • G. Iatì A.O.U. “G. Martino” Operative Unit of Radiation Oncology, Messina, Italy
  • M. Venza Department of Experimental Medical-Surgical, Specialized and Dentistry, University of Messina, Messina, Italy
  • N. Settineri A.O.U. RR “Papardo-Piemonte” Department of Medical Physics, Messina, Italy
  • S. Comitini A.O.U. “Cannizzaro” Department of Plastic Surgery, Catania, Italy
  • S. Pergolizzi Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy
Abstract:

Background: Keloids are benign fibrous dermal tumors originating from skin injury after surgery, piercing or others wounds. Materials and Methods: Sixty-two patients with keloids were treated postoperatively using orthovoltage irradiation. The total dose delivered was 12 Gy in three consecutive days, 4Gy per fraction. Treatment started 24 h after surgery. The median follow-up was 44.5 months. Results: Grade 1 erythema was observed in 48% of patients (30/62) 20/62 patients (32%) showed telangiectasia and altered skin pigmentation as late toxicities. In 10/62 (16%) a clinical relapse was observed. Conclusion: The postoperative orthovoltage radiotherapy for keloids is a valid and tolerated method that reduces the risk of recurrence. Aims: evaluate the role of post-operative superficial orthovoltage radiotherapy in the management of keloids.

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Journal title

volume 13  issue None

pages  201- 204

publication date 2015-07

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