Pnm-3: Abortion and Breast Cancer Risk: ACase-Control Study in Tehran, 2005

Background: Large part of research related to reproductive factors in breast cancer risk before and after menopause, a study case - control is that it factors in deliberate and spontaneous abortion in the two groups of women with breast cancer (cases) and non-infected women (control group) study, described odds ratio in women, breast cancer was measured. In this study, after recognizing the above factors in breast cancer risk in their separation, before menopause and after menopause were considered. Materials and Methods: 500 cases referred to shohadaye Tajrish Hospital and cancer Institute of Imam Khomeini hospital that they 250 premenopausal and 250 postmenopausal breast cancer patients were a select group method and continuous participation in the research was. The control group was composed of 500 persons during the study as visitor centers or with or referred to in the vicinity of group homes, women had lived in Tehran and sampling were selected in available or easy. Results: Employing logistic regression analysis and calculated the risk ratio findings showed: history of 2 spontaneous abortion (p=0.043 and OR=2.38) in total breast cancer wasn’t associated but separated before and after menopause correlation. Induced abortion in total (p=0.018 and OR=1.57) And at times before the menopause (p=0.018 and OR=2.03) were associated with breast cancer. Conclusion: According to the findings can be concluded that abortion is not itself a significant risk factor for breast cancer.