Phytochemistry and biologic activities of Caulerpa peltata native to Oman Sea

Authors

  • Abolfazl Barzegari Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
  • Hossein Nazemiyeh Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
  • Jaleh Barar Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Visiting Assistant Professor, Ovarian Cancer Research Center, School of Medicine, University of Pennsylvania, Philadelphia, USA
  • Nasrin Movahhedin Students’ Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran, Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of different mixture of solvents. A known alkaloid, caulerpin, was subsequently isolated from the fraction eluted by ethyl acatete100%. The antioxidant activity of all extracts was assessed by using the (DPPH) assay. Antiproliferative activity of the all extracts and caulerpin against the cancerous cell line was evaluated using MTT assay. General toxicity of extracts was determined using Brine Shrimp Lethality Assay (BSLA). Based on our results, a weak activity observed for all extracts in MTT assay, while they were toxic toward brine shrimp nauplii comparing to the podophylotoxin. This is the first report on phytochemistry and bioactivity of C.peltata which collected from Oman Sea.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Phytochemistry and Biologic Activities of Caulerpa Peltata Native to Oman Sea

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

full text

phytochemistry and biologic activities of caulerpa peltata native to oman sea

general toxicity, antiproliferative, antibacterial and antioxidant activities of caulerpa peltata j.v.lamouroux (caulerpaceae) collected from oman sea were investigated. dried, ground alga was soxhlet-extracted with hexane, dichloromethane and methanol successively. the methanol extract was subjected to vacuum liquid chromatography (vlc) fractionation on silica gel using a step gradient of diff...

full text

native speaker norms and teaching english to non_native speakers : the case of iranian efl learners

امروزه، این که زبان انگلیسی سریع ترین و گسترده ترین زبان مورد استفاده در سراسر جهان است به عنوان یک واقعیت پذیرفته شده است. استفاده مشترک از زبان انگلیسی به عنوان یک زبان بین المللی مستلزم هنجارها و مدل های یادگیری و تدریس زبان است. زبان شناسان توجه ویژه ای به مفهوم "زبان مادری" به عنوان تنها منبع درست و قابل اعتماد از داده های زبان می داده اند.با این حال، این اصطلاح به اندازه کافی روشن به نظر ...

15 صفحه اول

contribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.

this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...

15 صفحه اول

Elsholtzia: phytochemistry and biological activities

Plants of the genus Elsholtzia (Lamiaceae) have a long history of medicinal use in folk. The phytochemical investigations revealed the presence of flavonoids, phenylpropanoids, terpenoids, and other compounds. Abundant volatile components are also identified. Pure compounds, volatile constituents and crude extracts from the genus exhibited a wide spectrum of in vitro and in vivo pharmacological...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 13  issue 2

pages  515- 521

publication date 2014-06-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023