Physicochemical study on some cycloltexa peptide nano rings at body normal temperature; novel biodegradable and biocompadble vectors in drug delivery

Authors

  • B. Khalili Hadad -
  • K. Parivar -
  • M. Sayadian -
  • P. Yaghmaei -
Abstract:

Nanopartmles have been used as an approach to improve the pharmacodynamic and phannacokinetie propertiesof various drues. Amino acids have been considered to be useful to make such nano particles because ofthocompatithe and biodegradable characteristic. The quantum mechanical method that was chosen to analyze inethio hexa peptide nano ring]. The structure of some peptide nanorrigs as well as their dipole moments andenergies have been studied by quantum chemical calculations within the Ousager self-consistent reaction field(SCRF) model zing a Hartree-Fock method (RHF) at the RIIF/STO-30 (5D-7F). Radius of Gyration, Dipolemoment and Ramachandnm Plot are obtained to analyze the physicochemical characteristics of eyelo hexapeptide nano rings. These rings are studied concerning the utilization as nanovehicles.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

physicochemical study on some cycloltexa peptide nano rings at body normal temperature; novel biodegradable and biocompadble vectors in drug delivery

nanopartmles have been used as an approach to improve the pharmacodynamic and phannacokinetie propertiesof various drues. amino acids have been considered to be useful to make such nano particles because ofthocompatithe and biodegradable characteristic. the quantum mechanical method that was chosen to analyze inethio hexa peptide nano ring]. the structure of some peptide nanorrigs as well as th...

full text

Micro and nano-fabrication of biodegradable polymers for drug delivery.

This paper presents state-of-the-art micro and nano-fabrication techniques for biodegradable polymers. Replication molding, using a rigid or elastic master, can pattern structures on a polymer surface in a submicron resolution at a low cost. Layer-by-layer rapid prototyping methods are promising in producing controlled release units with complicated geometries, release mechanisms and the abilit...

full text

Peptide and Protein Delivery at a Glance

Peptide and protein drugs have found an important position in therapeutics. Recent advances in pharmaceutical biotechnology have led to an increase in the number of protein products in the market. As these therapeutic proteins and peptides are made available, it will be essential to formulate these drugs into safe and effective delivery systems. The twenty different naturally occurring amin...

full text

Peptide and Protein Delivery at a Glance

Peptide and protein drugs have found an important position in therapeutics. Recent advances in pharmaceutical biotechnology have led to an increase in the number of protein products in the market. As these therapeutic proteins and peptides are made available, it will be essential to formulate these drugs into safe and effective delivery systems. The twenty different naturally occurring amin...

full text

The effect of polylactic acid support in stability and electrical field of heterocyclic coupled hexa peptide nano systems: A novel strateu to drug delivery

Biological materials. recently. are the building blocks of several self-assembling peptide and protein systems.The main challenge In molecular self-assembly is to design molecular building blocks that can undergospontaneous organization. These cyche peptides were produced by an alternating fl'ell number of D- and Laminoacids.which interact through non-covalent interactions co an array of selfas...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue 4

pages  49- 58

publication date 2010-02-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023