P80: Imaging Action Potentials with Calcium Indicators Fura-4 in Motor Neuron Like Cells Derived Adipose Stem Cells
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p80: imaging action potentials with calcium indicators fura-4 in motor neuron like cells derived adipose stem cells
cell replacement therapy has provided the basis for future clinical applications to treat central nervous system injury, a common result of car accidents. induced functional motoneurons are an option for replacing the lost motoneurons. adipose derived stem cells (adscs) are an appropriate source of cells for autologous cell therapy with the ability of neural differentiation. in this study, adsc...
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Background: Adult stem cells (ASC) are undifferentiated cells found throughout the body. These cells are promising tools for cell replacement therapy in neurodegenerative disease. Adipose tissue is the most abundant and accessible source of ASC. This study was conducted to evaluate effect of selegiline on differentiation of adipose-derived stem cells (ADSC) into functional neuron-like cells (NL...
full texttrans-differentiation of the adipose tissue-derived stem cells into neuron-like cells expressing neurotrophins by selegiline
background: adult stem cells (asc) are undifferentiated cells found throughout the body. these cells are promising tools for cell replacement therapy in neurodegenerative disease. adipose tissue is the most abundant and accessible source of asc. this study was conducted to evaluate effect of selegiline on differentiation of adipose-derived stem cells (adsc) into functional neuron-like cells (nl...
full textImaging action potentials with calcium indicators.
The understanding of neuronal circuits has been, and will continue to be, greatly advanced by the simultaneous imaging of action potentials in neuronal ensembles. This protocol describes "bulk" loading of brain slices with acetoxymethyl (AM) ester calcium indicators in order to monitor action potential activity in large populations of neurons simultaneously. The imaging of calcium influx into n...
full textDifferentiation of Mesenchymal Stem Cells Derived From Human Adipose Tissue into Cholinergic-like Cells: In Vitro Study
Introduction: Cholinergic-associated diseases currently constitute a significant cause of neurological and neurodegenerative disabilities. As the drugs are not efficient in improving the suffered tissues, stem cell treatment is considered an effective strategy for substituting the lost cells. Methods: In the current study, we set out to investigate the differentiation properties of human adip...
full textDifferentiation of Adipose-derived Stem Cells into Schwann Cell Phenotype in Comparison with Bone Marrow Stem Cells
Objective(s) Bone marrow is the traditional source of human multipotent mesenchymal stem cells (MSCs), but adipose tissue appears to be an alternative and more readily available source. In this study, rat adipose-derived stem cells (ADSCs) were induced to differentiate into Schwann-like cells and compared with rat bone marrow stem cells (BMSCs) for their Schwann-like cells differentiation pote...
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Journal title
volume 2 issue 4
pages 130- 130
publication date 2014-12
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