P47: Application of Induced Pluripotent Stem Cells in Spinal Cord Injury Treatment
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p47: application of induced pluripotent stem cells in spinal cord injury treatment
stem cell therapy can be useful for spinal cord injury (sci). induced pluripotent stem cells (ipscs) are generated by reprogramming mature, fully differentiated cells into a pluripotent state. the ability to generate pluripotent cells from adult somatic cells without the need for an embryo was a major development in stem cell biology. ipscs were established from mouse fibroblasts and demonstrat...
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Spinal cord injury (SCI) is a neurologic disorder that have a significant impact on quality of life, life expectancy, and economic burden. SCI leads to irreversible neuronal loss and ultimately leads to paralysis. Mesenchymal stem cells (MSCs) are a promising source for cellular therapy because they have possessed the capacity of self-renewal and differentiation to several distinct mesenchymal ...
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full textInduced Pluripotent Stem Cells for Traumatic Spinal Cord Injury
Spinal cord injury (SCI) is a common cause of mortality and neurological morbidity. Although progress had been made in the last decades in medical, surgical, and rehabilitation treatments for SCI, the outcomes of these approaches are not yet ideal. The use of cell transplantation as a therapeutic strategy for the treatment of SCI is very promising. Cell therapies for the treatment of SCI are li...
full textp14: therapeutic potential of induced pluripotent stem cells for spinal cord injury
spinal cord injury (sci) is a destructive event that often lead to permanent neurologic deficit. current clinical treatments are aimed at preventing secondary damage, promoting regeneration, and replacing destroyed spinal cord tissue, although effective treatments for sci remain limited. cell therapies for treating sci are promising therapy for replacing dead cells, neuroprotection and axon reg...
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Journal title
volume 2 issue 4
pages 97- 97
publication date 2014-12
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