P-60: Relationship between Varicocele Surgery and Males' Infertility Based on Semen Analysis

Background: Semen quality is affected by environmental and genetically factors. The present study aimed to determine the association of varicocele surgery and males&#039; infertility based on semen analysis. Materials and Methods: In this case-control study, 188 men with infertility disorder in Ilam province were enrolled between May 2008 and May 2009. Semen analysis was done using the Weili Dynamic Sperm Analysis software adapted to WHO classification. This software, categories the sperm activities into four groups A-D based on speed and direction. In group A, sperms have normal speed and direct movement, while in group D, the sperms are motionless. Participants were stratified into two groups of cases with history of varicocele surgery (n=59) and controls without history of varicocele surgery (n=129). Collecting data were analyzed using SPSS software (version 16). The Kolmogorov-Smirnov test was used for distribution normality of data. Results: Mean age ± SD for cases and controls were 28.0 ± 3.4 years and 30.9 ± 5.5 years respectively (p>0.05). There was no significant relationship between class A, class A+B and live ration (p>0.05). Overall,72.9%, 74.6% and 62.7% of cases had difficulties in class A, class A+B and live ratio, respectively. Whereas, the corresponding rates for control group were 66.7%, 63.6% and 45%, respectively. However, this difference was significant only for live ratio (p<0.02). Conclusion: The quality of semen was reduced in men with history of varicocele surgery leading to infertility.