P-201: Relation between AMH Levels and Ovarian Response in ART Cycles
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Abstract:
Background: Ovarian reserve and ovarian response both are of the most important key factors in infertility treatment. Anti mullerian hormone (AMH) is one of lab tests that can predict ovarian reserve. relation between this assay and ovarian response can guide physition to choose the best protocol for the worst reserve. Materials and Methods: In a prospective cohort study, 110 infertile women (21-40 years old) who were candidate for ICSI attending assisted fertility unit,MAHDIEH hospital,TEHRAN,IRAN,from 2011-2012 were enrolled in this study.At first (day 2-4 of mense) serum level of AMH,FSH,ESTRADIOL were checked, then standard long protocol with GnRh agonist and then stimulation with HMG (merional 75 IU, IBSA) started. dose of HMG was based on patient age (standard protocol of our infertility ward). After ovum pickup,number of oocyte and embryo were recorded and 14 day after embryo transfer BHCG was cotroled. Analysis of data was done by using spss version 18 software. Results: The mean of AMH level was 3.9 nmol/ml (0.1-22.1) and mean of oocyte and embryo was11.29 (1-42) and 6.1(0-19) respectively. There was positive correlation between AMH levels and number of ovums and embryos. 9% of all cycles were cancelled because of ovarian unresponsiveness and in this group AMH was <0.67 nmol/ ml.regression analysis of data shows that AMH <0.75 nmol/ml was compatible with lower ovarian response(<4 oocyte) Conclusion: AMH level in day 2-4 of non stimulated cycle has positive correlation with ovarian response and AMH<0.75 nmol/ml was compatible with poor ovarian reserve.
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Journal title
volume 8 issue 2.5
pages 212- 212
publication date 2014-07-01
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