P-134: Effect of Tribulus Terrestris Extract on Sperm Parameters in Male Mouse

Background Spermatogenesis is a process in which the gametes are produced. Dysfunction in any of part of the process could result in infertility. Tribulus terrestris is a flowering plant which traditionally is used to sexual instinct. Reports indicate that this plant could elevate blood levels testosterone and enhance libido. MaterialsAndMethods In this experimental study, twenty six mature inbred male balb/c mice with average weight of 20g and age of 6 weeks were used. Animals were treated by Alcoholic extract of Tribulus terrestris flowers once daily for 8 weeks. After the last treatment, the mice were sacrificed. Semen samples were extracted from testis and epididymis tissue and were assessed by CASA. Results Clinical data indicated that median of weight gain in treated mice was statistically higher than non-treated ones. Besides, a significant difference in the number and motility of sperms from treated and non-treated mice was observed. Conclusion Results revealed that treatment with Tribulus terrestris extract can improve sperm parameters in mice. According to our previous knowledge, using Tribulus terrestris could result in sexual wellbeing as well as inducement more testosterones, and also erection in laboratory animals. This presumably means that this herb could affect human sperm parameters as well.