P-107: Can Combination of Hysterosalpingography and Ultrasound Replace Hysteroscopy in Diagnosis of Uterine Malformations in Infertile Women?

Background Müllerian anomalies are associated with infertility. Hysteroscopy as the gold standard of evaluating Müllerian anomalies is an invasive, expensive and risky procedure which requires enough experience. Transvaginal sonography (TVS) and hysterosalpingography (HSG) are less invasive procedures, but their accuracy is unknown. The aim of this study was to compare the accuracy of combination of TVS and HSG with hysteroscopy. MaterialsAndMethods Medical records of an infertile population who were undertaken all three diagnostic modalities were reviewed concerning their sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Results Ninety nine infertile women with the mean age of 29.1 ± 6.47 years, mean duration of marriage of 8.93 ± 10.28 years, and mean duration of infertility of 5.59 ± 4.16 years were assessed. The sensitivity, specificity, PPV, and NPV of TVS were 39.6, 76.5, 61.3, and 57.3%, respectively. HSG had a sensitivity of 39.6%, specificity of 96%, PPV of 90%, and NPV of 62.8%. When both modalities were combined, the sensitivity, specificity, PPV, and NPV were 60, 72.5, 67.4, and 66%, respectively.The diagnostic accuracy of single or combined techniques was similar. Conclusion 2D TVS, HSG, and combination of both diagnostic modalities are not accurate enough for assessing uterine malformation in infertile women.