Oxidative coupling of thiols to disulfides in solution radiation with Trimethylammonium Fluorochromate(VI), [(CH3)3NH[CrO3F], on Silica Gel

author

  • Shahriar Ghammamy Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran
Abstract:

A mild and efficient method for the oxidative coupling of thiols by trimethylammonium fluorochromate(TriMFC) in solution is reported. Trimethylammonium fluorochromate is efficient and new reagent, whichprepares easily and oxidizes thiols to the corresponding disulfides quickly. The reactions perform cleanly andcontrolled to stop at the disulfide stage without over-oxidation side products.

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Journal title

volume 5  issue 3

pages  173- 176

publication date 2012-09-20

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