Optical Spectroscopic Methods to Discriminate in-Vitro Hodgkin Cancerous and Normal Tissues
Authors
Abstract:
Simultaneous laser induced- breakdown spectroscopy (LIBS) and acoustic response techniques as well as Laser induced fluorescence (LIF) are applied to investigate the abnormal lymph tissues due to Hodgkin disease. The spectral shift in the emissive fluorescence of the cancerous tissues has been observed respect to the normal ones. Regarding LIBS, the concentrations of Ca and Na trace elements have been identified to be higher in the cancerous samples. In addition, the acoustic response of cancerous tissues has been elevated against healthy ones. The distinct differences in the spectra are taken into account for early and the rapid identification and diagnosis.
similar resources
Time-resolved fluorescence polarization anisotropy and optical imaging of Cybesin in cancerous and normal prostate tissues
Time-resolved polarization-dependent fluorescence of Cybesin in solution and in cancerous and normal prostate tissues were measured. The polarization preservation property of Cybesin in tissue was observed. The fluorescence intensity emitted from a Cybesinstained cancerous tissue area was found to be much stronger than that from a Cybesin-stained normal tissue area indicating that cancerous pro...
full textImmunohistochemical profile of ING3 protein in normal and cancerous tissues
The inhibitor of growth family, member 3 (ING3) protein may be capable of blocking the cell cycle via activating p53-transactivated promoters of p21 and Bcl2-associated X protein, and may induce apoptosis via a Fas/caspase-8-dependent signaling pathway. In the present study, immunohistochemistry was performed in order to characterize the expression profile of ING3 protein in tissue microarrays ...
full textNonlinear Optical Microscopy for Histology of Fresh Normal and Cancerous Pancreatic Tissues
BACKGROUND Pancreatic cancer is a lethal disease with a 5-year survival rate of only 1-5%. The acceleration of intraoperative histological examination would be beneficial for better management of pancreatic cancer, suggesting an improved survival. Nonlinear optical methods based on two-photon excited fluorescence (TPEF) and second harmonic generation (SHG) of intrinsic optical biomarkers show t...
full textDifferentiation of normal and cancerous lung tissues by multiphoton imaging.
We utilize multiphoton microscopy for the label-free diagnosis of noncancerous, lung adenocarcinoma (LAC), and lung squamous cell carcinoma (SCC) tissues from humans. Our results show that the combination of second-harmonic generation (SHG) and multiphoton excited autofluorescence (MAF) signals may be used to acquire morphological and quantitative information in discriminating cancerous from no...
full textApplication of small angle X-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues
ABSTRACT Background: Coherent scattering leads to diffraction effects and especially constructive interferences. Theseinterferences carry some information about the molecular structure of the tissue. As breast cancer isthe most widespread cancer in women, this project evaluated the application of small angleX-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues....
full textrole of optical spectroscopic methods in neuro-oncological sciences
in the surgical treatment of malignant tumors, it is crucial to characterize the tumor as precisely as possible. the determination of the exact tumor location as well as the analysis of its properties is very important in order to obtain an accurate diagnosis as early as possible. in neurosurgical applications, the optical, non-invasive and in situ techniques allow for the label-free analysis o...
full textMy Resources
Journal title
volume 9 issue None
pages 65- 72
publication date 2015-11
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023