Obstructive sleep apnea and the severity of coronary artery disease

Authors

  • Ali Vasheghani-Farahani Cardiac Primary Prevention Research Center (CPPRC), Tehran Heart Center, Tehran University of Medical Sciences Tehran, Iran
  • Fatemeh Kazemnejad Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Haleh Ashraf Cardiac Primary Prevention Research Center (CPPRC), Tehran Heart Center, Tehran University of Medical Sciences Tehran, Iran
  • Mohammad Alidoosti Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Parya Tavakoli poor Obesity Research Center, Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Soleil Saadat Sina trauma research center, Tehran University of Medical Sciences, Tehran, Iran
  • Tahereh Yazdani Obesity Research Center, Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Vahid Ghasem Amooeian Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abstract:

Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography. Methods: This study included 337 patients undergoing diagnostic coronary angiography at Tehran Heart Center, Iran. The Gensini score was obtained from each patient for coronary angiogram, and OSA were assessed by using Multivariable apnea prediction (MAP) risk index on the day of cardiac catheterization. The Gensini scores increased in accordance with increases in the MAP value. Results: The prevalence rates of three-vessel disease were 68.0% in OSA group and 32.0% in non-OSA group. The MAP index was the most significant independent determinant for the Gensini score. Conclusions: The independent association between OSA and CAD, even after adjustment for traditional confounders, suggests that, OSA should be taken into account when considering risk factors for CAD.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease

Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.Materials & Methods: This cross-sectional study was conducted on adult patients with forced...

full text

Obstructive sleep apnea and coronary artery disease.

In the recent years intensive research has revealed numerous negative consequences of obstructive sleep apnea (OSA) for the cardiovascular system. The pathophysiological interaction between OSA and coronary artery disease is complex and comprises neural, humoral, mechanical and haemodynamic components. One of the most important effects of OSA is an increase of sympathetic nerve traffic, which p...

full text

Obstructive sleep apnea, diagnosed by the Berlin questionnaire and association with coronary artery disease severity

BACKGROUND Obstructive sleep apnea syndrome (OSAS) is a highly prevalent sleep-related disorder that is associated with increased risk of hypertension (HTN) and coronary heart disease. This study aimed to evaluate the correlation between the OSAS and coronary artery disease (CAD) severity. METHODS The cross-sectional study was conducted from September 2012 to December 2013. We enrolled 127 pa...

full text

[Obstructive sleep apnea and risk factors for coronary artery disease].

STUDY AIM Obstructive sleep apnoea (OSA) is strongly associated with obesity, especially abdominal obesity. Obesity in turn is a well-known risk factor for coronary artery disease (CAD). The aim of our study was to evaluate the relationship between OSA severity and CAD risk factors. MATERIAL AND METHODS The sample consisted of 73 subjects (mean age +/- SE, 46.7 +/- 1 years) referred to a slee...

full text

determination of the relationship between severity of obstructive sleep apnea and chronic obstructive pulmonary disease

introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 9  issue None

pages  276- 282

publication date 2018-05

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023