Observation of Nocardia Asteroides Complex in a Patient with Corneal Ulceration: The First Case Report from Iran

Authors

  • Bagher Hoseini Pathologist, Iran Eye Bank, Tehran, Iran
  • Masoumeh Rasouli-Nasab Ph.D. Candidate of Microbiology, Psteur Insititute, Tehran, Iran
  • Mehdi Fatahi-Bafghi Assistant Professor, Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Parvin Heidarieh Assistant Professor of Microbiology, Department of Bacteriology & Virology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
  • Seyedeh Zeinab Seyyed-Yousef Postgraduate Student of Microbiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Seyyed Saeed Eshraghi Professor, Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Shadi Habibnia Ph.D. Candidate of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:

Background & Aims: Nocardia asteroides is gram-positive, partially acid-fast, aerobic actinomycetes which cause a wide range of skin infections, and pulmonary, cerebral, and ocular infection. Case Presentation: A 60-year-old man with diabetes presented with ocular ulcers in 2015. Through the medical records evaluation, physical examination, and biochemical evaluation of the patient, Nocardia asteroides complex was identified as the cause of infection. The patient was treated with amikacin and ciprofloxacin, and recovery was obtained and the patient was placed on the waiting list for corneal transplantation. Conclusion: Diagnosis of keratitis caused by Nocardia asteroides is difficult and it may be misdiagnosed due similarities with keratitis caused by nontuberculous mycobacteria (NTM). Therefore, suitable diagnosis methods and early diagnosis of ocular nocardiosis are necessary. In the present study, Nocardia asteroides complex was isolated from a corneal ulceration.

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Journal title

volume 23  issue 2

pages  228- 233

publication date 2016-03-01

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