O-23: Transfer of Blastocysts Derived from Frozen Thawed Cleavage Stage Embryos Improved Ongoing Pregnancy

Authors

  • Aflatoonian A
  • Eftekhar M
Abstract:

Background: The aim of our study was to compare the resulting from transfer of embryos that cryopereserved in cleavage stage after thawing and transfer of embryos after thawing and culture in sequentional media until blastocyst formation. Materials and Methods: In this prospective clinical study, we have evaluated 128 cycles in women undergone in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) with embryo cryopreservation. Exclusion criteria were women with age >35 years; BMI >30; history of Diabetes Mellitus; thyroid disease; history of sever endometriosis. Frozen embryos were thawed and then cultured in sequential media until blastocyst stage in blastocyst group and were compared with thawed embryos in cleavage stage group. Results: Implantation rate was significantly higher in blastocyst group 30% compared to 17% in cleavage group. No statistically differences were reported in chemical and clinical pregnancy rates. Ongoing pregnancy rate was significantly higher in blastocyst group 42.9% compared to 24.6% in cleavage group (p=0.023). Conclusion: Our results indicated that blastocyst formation after thawing of cleavage stage embryos is a good predictor for embryo viability and pregnancy outcome.

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Journal title

volume 6  issue 2

pages  -

publication date 2012-09-01

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