Nanotechnology for peripheral nerve regeneration

nanotechnology for peripheral nerve regeneration

peripheral nerve injuries (pni) can lead to lifetime loss of function and disfigurement. different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. utilization of absorbable and non-absorb...

Electrical stimulation for promoting peripheral nerve regeneration.

The peripheral nervous system has the intrinsic capacity to regenerate axons into target tissues, and peripheral nerves severely damaged or transected can be reconstructed by microsurgical techniques. The aim of peripheral nerve surgery is to pave way for fast and most possible thorough functional recovery. However, full functional recovery is rarely seen and several reasons for this have alrea...

Preparation of acellular sciatic nerve scaffold and it’s mechanical and histological properties for use in peripheral nerve regeneration

Background: Tissue engineering is a developing multidisciplinary and interdisciplinary field involving the use of bioartificial implants for tissue remodeling with the target for repair and enhancing tissue or organ function. Acellular nerve has been used in experimental models as a peripheral nerve substitute. The purpose of the present study was to evaluate the mechanical and histological cha...

Bioengineered Scaffolds for Peripheral Nerve Regeneration

BIOHYBRID - Biohybrid templates for peripheral nerve regeneration.

Dear Editor, Peripheral nerve injuries represent a major cause for morbidity and disability in affected patients and cause substantial costs for society in a global perspective. It has been estimated that peripheral nerve injuries affect 2.8% of trauma patients, many of whom acquire lifelong disability (Noble et al., 1998). With respect to an incidence of nerve injuries of 13.9/100,000 inhabita...