Nanoencapsulation and delivery of curcumin using some carbohydrate based systems: A review

Authors

  • Bizhan Malaekeh-Nikouei Nanotechnology Research Center, Institute of Pharmaceutical Technology, Mashhad University of Medical Sciences, Mashhad, Iran
  • Davoud Salarbashi School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran| Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
Abstract:

Nanoencapsulation is commonly used to improve nutritional properties, rheological behavior and flavor profile of phytochemicals. The particles commonly utilized to encapsulate the functional ingredients are natural polymers such as polysaccharides and proteins. There is an ever-growing interest for use of polysaccharides to encapsulate hydrophobic phytochemicals like curcumin. Curcumin is a polyphenol compound with numerous health benefits including anti- inflammatory, antioxidant capacity and anti-cancer activity. However, poor solubility of this compound in gut has been led to restricting of its bio accessibility. Encapsulation of curcumin with biopolymers is one of the most effective methods to increase its bioavailability. In the present article, we will briefly review the recent studies focused on application of carbohydrate polymers including starch, β-cyclodextrin, pectin, Arabic gum, carrageenan gum, soluble soy bean polysaccharide (SSPS) and Enteromorpha prolifera polysaccharide as a carrier of curcumin.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Nanoencapsulation for drug delivery

Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs. Targeting of NCs can enhance the accumulation of nanonencapsulated drug at the diseased site. This article focussed on the...

full text

Microencapsulation and Nanoencapsulation: A Review

ABSTARCT Encapsulation is a process of enclosing the substances within an inert material which protects from environment as well as control drug release. Recently, two type of encapsulation has been performed in several research. Nanoencapsulation is the coating of various substances within another material at sizes on the nano scale. Microencapsulation is similar to nanoencapsulation aside fro...

full text

construction and validation of a computerized adaptive translation test (a receptive based study)

آزمون انطباقی رایانه ای (cat) روشی نوین برای سنجش سطح علمی دانش آموزان می باشد. در حقیقت آزمون های رایانه ای با سرعت بالایی به سمت و سوی جایگزین عملی برای آزمون های کاغذی می روند (کینگزبری، هاوسر، 1993). مقاله حاضر به دنبال آزمون انطباقی رایانه ای برای ترجمه می باشد. بدین منظور دو پرسشنامه مشتمل بر 55 تست ترجمه میان 102 آزمودنی و 10 مدرس زبان انگلیسی پخش گردید. پرسشنامه اول میان 102 دانشجوی س...

Novel curcumin oral delivery systems.

Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L), has proven to be a modulator of multiple intercellular signalling pathways linked to inflammation, to proliferation, growth, invasion, drug sensitivity, angiogenesis and metastasis of cancer cells. Although curcumin has shown significant efficacy in cell culture studies, it has shown limited efficacy in clinical ...

full text

A Review of Vesicular and Polymeric Nano-systems in Olanzapine Drug Delivery

 Olanzapine (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno [2, 3-b][1, 5]benzodiazepine) is an antipsychotic drug with poor water-solubility that has a suitable affinity to some receptors. This benzodiazepine derivative is a new (atypical) antipsychotic drug and has a wide range of efficacy, especially in treatment of patients with negative psychiatric symptoms of schizophrenia. Olanzapine is ...

full text

Review Article Curcumin (diferuloylmethane) Delivery Methods: A Review

Curcumin interacts with a large number of extraand intracellular targets in a biphasic dose-dependent manner. It controls inflammation, oxidative stress, cell survival, cell secretion, homeostasis, and proliferation. Its mechanisms of action are generally directed toward cells that exhibit disordered physiology or blatant mutation-based abnormal states. Optimizing preventative or therapeutic ap...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 5  issue 2

pages  57- 61

publication date 2018-04-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023