Muscle perfusion scan for prediction of anticipated diabetic foot ulceration
Authors
Abstract:
Introduction:We evaluated the performance of muscle perfusion scan (MPS) to assess muscle perfusion reserve (MPR) for prediction of incident diabetic foot ulcerations (DFU). Methods: We recruited 41 diabetic patients without any history of DFU. Five mCi 99mTc-MIBI was injected intravenously during repetitive dorsal and plantar right foot flexions. Then posterior calves were imaged and the counts of the region of interests (ROI) over the right and left calves were collected. MPR was calculated as the percentage of counts of right calf ROI–counts of left calf ROI / counts of left calf ROI. Six patients did not complete the study, 3 of them due to technical errors. Patients were followed for possible occurrence of DFU for at least 12 months. Results: During the 563±84 (range: 309-633) days follow up period, 2 patients developed DFU (5.7%). MPR was insignificantly lower in patients who developed foot ulceration in comparison to those without foot ulceration (11.3±0.6 % vs. 63.4±40.8 %; p=0.08). The cutoff at first decile of MPR values (i.e. 16%) discriminated the patients with and without future DFU with accuracy of 92% (OR= 3; p-Value=0.005). Conclusion: MPS is useful to detect patients with diabetes at risk for future DFU.
similar resources
muscle perfusion scan for prediction of anticipated diabetic foot ulceration
introduction:we evaluated the performance of muscle perfusion scan (mps) to assess muscle perfusion reserve (mpr) for prediction of incident diabetic foot ulcerations (dfu). methods: we recruited 41 diabetic patients without any history of dfu. five mci 99mtc-mibi was injected intravenously during repetitive dorsal and plantar right foot flexions. then posterior calves were imaged and the count...
full textIssues with Diabetic Foot Ulceration
The majority of foot ulcers appear to result from minor trauma in the presence of sensory neuropathy. This best describes the critical triad most commonly seen in patients with diabetic foot ulcers: peripheral sensory neuropathy, deformity, and trauma. All three of these risk factors are present in 65% of diabetic foot ulcers. Calluses, edema, and peripheral vascular disease have also been iden...
full textPatient education for preventing diabetic foot ulceration.
Treatment of diabetic foot ulceration is very challenging, costly and often needs to be of long duration. This leads to substantial economic burden. Population-based research suggests that a meaningful reduction of the incidence of amputations caused by diabetes mellitus has already been achieved since the St. Vincent resolution in 1989. Still, it cannot be inferred from these studies that the ...
full textTopical haemoglobin spray for diabetic foot ulceration.
UNLABELLED The development and subsequent deterioration of diabetic foot ulceration (DFU) is a common occurrence across all healthcare divides, concerning all patient groups, age, gender and social environments. It increases demand on clinical resources and creates unnecessary hardship for patients. Chronic DFU is challenging to prevent and notoriously difficult to manage owing to the complex n...
full textWound Measurement in Diabetic Foot Ulceration
In this chapter the authors aim to provide a brief introduction to wound assessment in the diabetic foot and discuss the role of wound measurement within that assessment process. A literature review describing wound measurement in diabetic foot wounds was conducted and a review of wound measurement tools and techniques reported. The results of a wound measurement study using a particular techni...
full textMy Resources
Journal title
volume 25 issue Supplement 1
pages 35- 39
publication date 2017-02-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023