Microwave assisted green synthesis of α, ά- bis (substituted- benzylidene) alkanones

microwave assisted green synthesis of α, ά- bis (substituted- benzylidene) alkanones

microwave assisted green synthesis of α, ά- bis (substituted- benzylidene) alkanones by the crossed- aldol condensation reaction of substituted aryl aldehydes with ketones in the presence of catalytic amount of nbcl5 in good to excellent yields. this reaction is carried out under solvent-free conditions. the results showed that aldehydes bearing electron–donating substituent's on phenyl-ring fa...

P-Dodecylbenzenesulfonic acid (DBSA), a Brønsted acidSurfactant Catalyst for Synthesis of α, ά-bis(substituted benzylidene)cycloalkanones with Electron-Withdrawing Substituent in Aqueous Media

An array of aromatic aldehydes with electron withdrawing groupunderwent crossed-Aldol condensation with cycloalkanone in the presence of catalytic amounts of DBSA under aqueous media to afford the corresponding α, ά-bis(substituted-benzylidene) cycloalkanones in good yields. The electronic effects on aromatic aldehydes could be observed. The present method is operationally simple and use of wat...

A facile solvent free Claisen-Schmidt reaction: synthesis of α,α'-bis-(substituted-benzylidene)cycloalkanones and α,α'-bis-(substituted-alkylidene)cycloalkanones.

Solvent-free Claisen-Schmidt reactions of cycloalkanones with various substituted benzaldehydes (aryl aldehydes) using solid NaOH (20 mol%) and applying a grinding technique were studied. Quantitative yields (96-98%) of α,α'-bis-(substituted-benzylidene)cycloalkanones were obtained. Aliphatic aldehydes also provided α,α'-bis-(substituted-alkylidene)cycloalkanones in very good yields with minor ...

An efficient synthesis of α,α'-benzylidene bis(4-hydroxycoumarin) derivatives catalyzed by Tl2O3 nanoparticles

In this work, we attempted to synthesize thallium (III) oxide nano structures by direct thermal decomposition using thallium I phenylsuccinic acid coordination polymer [Tl(PsucH)]n as a precursor. Also, Tl2O3 nanoparticles have been characterized by scanning electron microscopy (SEM), X-Ray powder diffraction (XRD) and IR spectroscopy and then we report a simple and efficient method for the syn...

An efficient synthesis of α,α'-benzylidene bis(4-hydroxycoumarin) derivatives catalyzed by Tl2O3 nanoparticles

In this work, we attempted to synthesize thallium (III) oxide nano structures by direct thermal decomposition using thallium I phenylsuccinic acid coordination polymer [Tl(PsucH)]n as a precursor. Also, Tl2O3 nanoparticles have been characterized by scanning electron microscopy (SEM), X-Ray powder diffraction (XRD) and IR spectroscopy and then we report a simple and efficient method for the syn...

p-dodecylbenzenesulfonic acid (dbsa), a brønsted acidsurfactant catalyst for synthesis of α, ά-bis(substituted benzylidene)cycloalkanones with electron-withdrawing substituent in aqueous media