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The phenotype and function of antigen-specific CD8 T cells are closely associated with the efficacy of a therapeutic vaccination. Here we showed that multiple immunizations with LCMV gp33-41 peptide (KAV) in Freund's adjuvant could induce KAV-specific CD8 T cells with low expression of CD127 and CD62L molecules. The inhibitory receptor PD-1 was also expressed on a substantial part of KAV-specif...
full textCalibration of the relative molecular mass of proteoglycan subunit by column chromatography on Sepharose CL-2B.
Calibration relationships were derived for cartilage proteoglycan subunit (PGS) that relate the inverse z-average hydrodynamic radius (Rs) and the weight-average Mr (Mw) to the partition coefficient (Kav.) for PGS when chromatographed on a Sepharose CL-2B column. PGS isolated from chick limb-bud chondrocyte cell cultures was fractionated chromatographically into eight pools, for which Mw and Rs...
full textProteoglycan synthesis in two murine bone marrow stromal cell lines.
There is evidence indicating that stromal proteoglycans are an important functional component of the hematopoietic microenvironment. Proteoglycan synthesis was therefore investigated in the MS3-2A and D2XRII hematopoietic stromal cell lines. These lines differ in their capacity to support hematopoiesis in vitro, D2XRII supporting in vitro hematopoiesis, whereas MS3-2A does not. Cells were label...
full textA History of Chinese Literature?
It is difficult enough to write the history of a national literature where this history is relatively short, as in Russian or American literature. The problem becomes exponentially larger with a national literature that spans three millennia, and, measured by sheer volume of text, might well be larger than all other national literatures combined. Yet writing a history of Chinese literature is n...
full textUrinary excretion kinetics of hydroxyethyl starch 350/0.60 in normovolaemic man.
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Journal title
volume 15 issue 37
pages 25- 46
publication date 2015-09
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