Is Gabapentin Effective on Pain Management after Arthroscopic Anterior Cruciate Ligament Reconstruc tion? A Triple Blinded Randomized Controlled Trial
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Abstract:
Background: Acute pain is common after arthroscopic surgeries and it is one of the most important causes of patient dissatisfaction, admission time and increased morbidity . Gabapentin with anti-hyperalgesic effects can play a critical role in pre-emptive analgesia methods. The aim of this study was to assess the efficacy of gabapentin in pain management after surgery and the rate of drug consumption in patients who are candidate for anterior cruciate ligament (ACL) reconstruction arthroscopic surgery. Methods: In this randomized, triple blind clinical trial, 114 patients who were candidate for arthroscopic ACL reconstruction were divided into two groups of gabapentin (G) and placebo (p), with 57 patients in each group. The intervention group received gabapentin 600 mg and a placebo was administered in control group. Patients received on-demand pethedine for pain management. The primary outcome was pain intensity according to the visual analogue scale (VAS) and the secondary outcome was the amount of opioid consumption and incidence of side effects (including: dizziness, sedation, nausea and vomiting) at 6 and 24 h visits. Results: The mean pain intensity in G group at both the 6 and 24 hour visits was significantly lower than the control group (Both p
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is gabapentin effective on pain management after arthroscopic anterior cruciate ligament reconstruc tion? a triple blinded randomized controlled trial
background: acute pain is common after arthroscopic surgeries and it is one of the most important causes of patient dissatisfaction, admission time and increased morbidity . gabapentin with anti-hyperalgesic effects can play a critical role in pre-emptive analgesia methods. the aim of this study was to assess the efficacy of gabapentin in pain management after surgery and the rate of drug consu...
full textIs gabapentin effective on pain management after arthroscopic anterior cruciate ligament reconstruction? A triple blinded randomized controlled trial.
BACKGROUND Acute pain is common after arthroscopic surgeries and it is one of the most important causes of patient dissatisfaction, admission time and increased morbidity . Gabapentin with anti-hyperalgesic effects can play a critical role in pre-emptive analgesia methods. The aim of this study was to assess the efficacy of gabapentin in pain management after surgery and the rate of drug consum...
full textAnalgesic Effect of Gabapentin on Post-Operative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction
To the Editor Mardani-Kivi et al presented results about a triple blinded randomized controlled trial with gabapentin in patients that underwent anterior cruciate ligament (ACL) reconstruction (1). In their manuscript, the introduction section is very illustrative about the subject. With respect to methodology, it is well known that the physical diagnosis of ACL injury is particularly difficult...
full textReply to "Analgesic Effect of Gabapentin on Post-Operative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction"
In Reply Dr. Ortiz and Dr. Romero-Quezada evaluated our study precisely and authors are grateful for their great survey on our article. There were some questions and concerns that we are going to answer. We wish it could help others to come up with better ideas and conclusions. 1. ACL tear may occur in two scenarios and we believe that there is not a third one: 1st- the ACL injury functionally ...
full textThe Use of Expert System in the Rehabilitation of Patients after Anterior Cruciate Ligament Arthroscopic Surgery: A Randomized Clinical Trial
Introduction: The Anterior Cruciate Ligament (ACL) plays a vital role in stabilizing the knee. ACL lesions cause joint instability and severe disturbances in physical function and balance. After ACL reconstruction surgery, patients' ability to perform daily activities is significantly reduced and rehabilitation programs are necessary. The objective of the present study was to use an expert syst...
full textThe Use of Expert System in the Rehabilitation of Patients after Anterior Cruciate Ligament Arthroscopic Surgery: A Randomized Clinical Trial
Introduction: The Anterior Cruciate Ligament (ACL) plays a vital role in stabilizing the knee. ACL lesions cause joint instability and severe disturbances in physical function and balance. After ACL reconstruction surgery, patients' ability to perform daily activities is significantly reduced and rehabilitation programs are necessary. The objective of the present study was to use an expert syst...
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Journal title
volume 1 issue 1
pages 18- 22
publication date 2013-09-01
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