International comparison of species of monkey used for the neurovirulence test for oral poliomyelitis vaccine

Authors

  • L. R. Boulger
  • P. Ahourai
  • S.A. Marsden
  • S.C. Arya
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International comparison of species of monkey used for the neurovirulence test for oral poliomyelitis vaccine.

The results of an international comparative study of the neurovirulence of oral poliomyelitis vaccines in three species of Old World Monkeys, viz. Macacus irus (cynomolgus), M. mulalla (rhesus) and Cercopithecus aelhiops (vervet) are pre3ented. The greate~t sensitivity to Sabin poliovaccine types 1 and IIr was shown by cynomolgus monkeys, followed by rhesus and vervet monkeys, whilst vervet mon...

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Journal title

volume 31  issue 1

pages  17- 28

publication date 1979-02-01

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