Immune Issues and Mechanisms in Cancer
author
Abstract:
The immunologic defense mechanism is well demontrated in neoplasia of animals and human. Spontaneous regression of many human tumors such as malignant melanomas, 1vmphosarcomas, neuroblastomas choriocarcinomas, adenocarcinomas and leukemias is due to the defense mechanism of lymphoretrcular system. The discovery of carcinoembrvonicantigen in carcinoma of gastrointestinal tract and the alpha-fetoprotein in hepatomas as well 89-recovery of antibodies against these antigens, prevalence of malignancies in immunodeficient patients who have received ellografts and iltmunosuppressiveagents;areall in favor of such defence mecbanism On the basis of the immunological reaction of the host against tumors many tests are developed for diagnosis of neoplasia; these tests include floccu lations, precipitations, tanned red cell agglutinations, immunofluorescence, and radioimmunoassay. Many kinds of malignancies are treated successfully
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Journal title
volume 4 issue 1
pages 1- 8
publication date 1975-10
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