Iatrogenic Cushing\'s Syndrome Due to Cutaneous Corticosteroid Therapy
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Abstract:
Summary A case of Cushing' s syndrome associated with application of topical clobetasol propionate (0.05%) is reported. Local application of clobetasol propionate is associated with adrenal suppression in normal subjects and on this basis, it has been recommended that less than 50 g per week be used. There have been sporadic case reports of cushing's syndrome associated with topical steroid but in all cases the amount applied was greater than 100 g per week, which would be considered excessive by present day guidelines. We report a well-documented example of this rare complication of the use of topical corticosteroid.
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Journal title
volume 17 issue 1
pages 42- 46
publication date 1993-03
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