Histopathological effects of acute copper sulphate exposure on kidney, liver and gill of common carp, Cyprinus carpio, fingerlings

In the present study histological effects of copper sulphate on, 180 common carp, Cyprinus carpio, fingerlings were studied. In this regard, fish of treatment groups were exposed to 2, 4, 6, 8 and 10 ppm of copper sulphate during 4 days. Behaviours and clinical signs of fish were recorded during the experiment, and samples were done from kidney, liver and gill of moribund and fresh dead fish, and specimens were studied after section and hematoxylin_ Eosin staining for histopathological signs. In this study LC50 value for 48 and 96 hours exposure were calculated as 6.3 and 4.9 mg/l, respectively for common carp fingerlings. Mild to severe histopathological signs were observed in kidney, liver and gill of all treatment fish specimens. Pathologic severity signs in sampled tissues were increased by increasing in concentration and exposure times of copper sulphate. According to the results, it is not recommended to use copper sulphate in fingerling common carp farms in dosage higher than 2 mg/l.