Helicobacter pylori infection: Clinical, Endoscopic and Pathological findings in Iranian children

Authors

  • Ahmad Khodadad Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Farzaneh Motamed Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Fatemeh Farahmand Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Golamhosein Fallahi Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Leila Arastoo Department of pediatrics, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Maryam Monajemzade Department of pediatric pathology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mehri Najafi Department of pediatric gastroenterology, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
  • Rana Doroudian Department of pediatrics, Children's Medical center, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:

Background: Helicobacter pylori (H.pylori) infection has an important role in promoting gastrointestinal disease in human. It may be acquired early in life, particularly in developing countries. The aim of this study is to evaluate the association between H.pylori infection and clinical manifestations in Iranian children.Materials and Methods: In this retrospective, cross-sectional study, H. pylori status was assessed by pathological examination of gastric biopsy in symptomatic children. A total of 266 patients were diagnosed as infected by H. pylori, compared with 268 uninfected patients matched by age and sex. Reported symptoms, endoscopic and pathological findings in the two groups were analyzed using chi square test. The limit of statistical significance was set at P

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Journal title

volume 2  issue 3.2

pages  9- 17

publication date 2014-08-01

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