Genotoxic and Carcinogenic Effect of Gutkha: A Fast-growing Smokeless Tobacco

Authors

  • Akashay Bhargava Assistant Professor, Department of Oral Maxillofacial Pathology, Government Dental College and Hospital, Jaipur, Rajasthan, India
  • Bharat Sankhla Assistant Professor, Department of Oral Maxillofacial Pathology, Government Dental College and Hospital, Jaipur, Rajasthan, India
  • Khushboo Kachhwaha Assistant Professor, Department of Oral Medicine and Radiology, Vyas Dental College and Hospital, Jodhpur, Rajasthan, India
  • Sayed Yawer Hussain Assistant Professor, Department of Dental Materials, Government Dental College and Hospital, Jaipur, Rajasthan, India
  • Shikha Saxena Assistant Professor, Department of Oral Maxillofacial Pathology, Government Dental College and Hospital, Jaipur, Rajasthan, India
  • Sundragiri Krishana-Sireesha Assistant Professor, Department of Oral Maxillofacial Pathology, Government Dental College and Hospital, Jaipur, Rajasthan, India
Abstract:

Oral cancer is a highly lethal disease and one of the most debilitating and disfiguring of all malignancies in the world. According to Global Adult Tobacco Survey (GATS) 2010 report, 60% of tobacco users in India use only smokeless tobacco. Among 206 million smokeless tobacco users, 65.1 million are consuming gutkha. In recent years, gutkha is recognized as a life threatening disorder with the serious health consequences. The aim of this review is to increase the attention to complete ban of tobacco use, awareness, knowledge, and beliefs of public about the harms of not only gutkha but also all other tobacco products and also to promote the intentions to quit the habits.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer

Smokeless tobacco consumption, which is widespread throughout the world, leads to oral submucous fibrosis (OSMF), which is a long-lasting and devastating condition of the oral cavity with the potential for malignancy. In this review, we mainly focus on the consumption of smokeless tobacco, such as paan and gutkha, and the role of these substances in the induction of OSMF and ultimately oral can...

full text

Report of gutkha (smokeless tobacco) use in children aged 10-12 years.

To cite: Mallikarjuna R, Gangwal RR, Shanthraj SL, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2012008319 DESCRIPTION Tobacco is a risk factor for six of the eight leading causes of deaths in the world and kills up to one-half of its users. Tobacco use can result in a number of oral diseases. Oral cancer, periodontitis 4 compromised wound healing, a red...

full text

Toxicity of Gutkha, a Smokeless Tobacco Product Gone Global: Is There More to the Toxicity than Nicotine?

The popularity of smokeless tobacco (ST) is growing rapidly and its prevalence of use is rising globally. Consumption of Gutkha, an addictive form of ST, is particularly common amongst South Asian communities throughout the World. This includes within the US, following large-scale immigration into the country. However, there exists a lack of knowledge concerning these alternative tobacco produc...

full text

Bidis and smokeless tobacco

Bidis and smokeless tobacco are the cheapest, least taxed and most commonly used tobacco products in India. They are highly addictive and high in carcinogens. They cause a broad spectrum of diseases; yet awareness about their ill-effects is low. Smokeless tobacco products containing arecanut, e.g. gutka and mawa, are especially addictive and carcinogenic. The high incidences of oral and lung ca...

full text

The carcinogenic profiles, trends, and cencer risks of regional smokeless tobacco products

Smokeless tobacco products have existed for centuries and vary significantly across geographical regions. The constituents found in each smokeless tobacco product depends on many factors, including social customs, manufacturing regulations, and the availability of local raw ingredients. Unfortunately, tobacco products have been linked to cancer over the past several decades, particularly of the...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 10  issue 1

pages  52- 63

publication date 2018-08-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023