Frequency and Antibiotic Resistance Pattern of Diarrheagenic Escherichia coli (DEC) Strains Isolated from Children Aged Less Than 10 Years
Authors
Abstract:
ABSTRACT Background and Objectives: Diarrheagenic Escherichia coli (DEC) pathotypes are important causes of diarrhea among children in developing countries. The objective of this study was to determine the frequency and antibiotic resistance pattern of DEC pathotypes in children aged less than 10 years. Methods: This cross-sectional study was done on 300 E. coli strains isolated from diarrheic stool samples of children aged less than 10 years who were admitted to hospitals and central laboratory in Zahedan, between July and October 2016. DEC pathotypes were identified by standard biochemical testing and phenotypic testing using polyvalent antiserums. Antibiotic resistant pattern of these strains was evaluated against 11 different antibiotics by the agar disk diffusion method according to the Clinical and Laboratory Standards Institute guidelines. Results: Of the 300 E. coli isolates, 89 (29.6%) were found positive for DEC using polyvalent antiserums. In this study, 35 cases (39.3%) reacted with antiserum 1, 21 cases (25.8%) reacted with the antiserum 2, and 31 cases (34.8%) reacted with antiserum 3. The highest rate of resistance was observed against ampicillin (94.8%), tetracycline (87.2%), and co-trimoxazole (70.5%). In addition, the lowest rate of resistance was related to imipenem (1%) and ciprofloxacin (8.9%). Conclusion: DEC pathotypes are the important causes of diarrhea among children admitted to hospitals of Zahedan. Considering the high rate of antibiotic resistance among these pathotypes in this region, prescription of antibiotics should be based on accurate detection of these strains. Keywords: Escherichia coli, Child, Antibiotic Resistance.
similar resources
Antibiotic Resistance in Diarrheagenic Escherichia coli Isolated from Broiler Chickens in Pakistan
Background: Diarrheagenic Escherichia coli (DEC) strains are predominant cause of gastrointestinal tract illnesses. The main objective of the study was to determine antibiotic resistance in various types of DEC isolated from chicken broilers farmed in Pakistan. Methods: A total of 200 feces and 200 meat samples from broiler chickens were collected from the slaughtering shops in Southern Punjab...
full textDetermination of antibiotic resistance pattern in Escherichia coli strains isolated from animal faeces in a farm house
The present study aimed to evaluate the antibiotic resistance pattern of Escherichia coli strains isolatedfrom animals to ascertain the levels of antibiotic resistance pervasiveness. A total of 28 E. coli strains wereisolated from faecal samples and the antibiotic resistance pattern of E. coli strains was determined by meansof disc diffusion assay. The resistance pattern determined for all stra...
full textMolecular characterization of diarrheagenic Escherichia coli isolated from children less than five years of age in Dar es Salaam, Tanzania
full text
Molecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia coli strains Isolated from Adults in Iran
Resistance to oxyimino cephalosporins antibiotics in Enterobacteriaceae is primarily done by the extended spectrum β-lactamases (ESBLs). Clear identification of risk factors for ESBL-producing infections is necessary. Therefore, efficient strategies can be developed to decrease outbreak of these infections. The aim of this study was to determine the antibacterial susceptibility and ESBLs patter...
full textMolecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia coli strains Isolated from Adults in Iran
Resistance to oxyimino cephalosporins antibiotics in Enterobacteriaceae is primarily done by the extended spectrum β-lactamases (ESBLs). Clear identification of risk factors for ESBL-producing infections is necessary. Therefore, efficient strategies can be developed to decrease outbreak of these infections. The aim of this study was to determine the antibacterial susceptibility and ESBLs patter...
full textAntibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd
Abstract Background Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. Material...
full textMy Resources
Journal title
volume 12 issue 2
pages 7- 12
publication date 2018-03
By following a journal you will be notified via email when a new issue of this journal is published.
No Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023