Fatty Acid Composition and Toxicity of Melia azedarach L. Fruits against Malaria Vector Anopheles stephensi

Authors

  • Abbas Hadjiakhoondi Department of Pharmacognosy, Medicinal Plant Research Center and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Hamid Reza Sadeghipour Roodsari Department of Physiology , Faculty of Medicine , Tehran University of Medical Sciences, Tehran, Iran
  • Hassan Vatandoost Department of Medical Entomology, School of Public Health and Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran
  • Mahnaz Khanavi Department of Pharmacognosy, Medicinal Plant Research Center and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Reza Abai Department of Medical Entomology, School of Public Health and Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran
  • Mohsen Vosoughi Department of Chemistry, Medicinal Plant Research Center and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Motahareh Kazemi Department of Pharmacognosy, Medicinal Plant Research Center and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
Abstract:

      The fruit of Melia azedarach L. (Meliaceae) was extracted with hexane, and its fatty acids methyl ester was analyzed using GC/MS. Thirteen components representing 85.1% of the total extract were identified. The major components identified were methyl palmitate (18.8%), methyl linolenate (16.1%) and methyl linoleate (9.8%). The fruits’ extract had a LC50 of 5.5 ppm against the larvae of Anophles stephensi.  

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Journal title

volume 2  issue 2

pages  97- 102

publication date 2006-04-01

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