Familial Mediterranean Fever (FMF): Mysterious Presentations and Challenging Points From Diagnosis to Management in Acute Care Settings; A Literature Review

Enigmas in familial Mediterranean fever (FMF).

Familial Mediterranean Fever: Review of Literature and Report of Two Cases

Familial Mediterranean fever, an autosomal recessive disorder, is a member of the periodic fever syndromes, and considered to be the most common cause of recurrent febrile episodes in children. It is important to understand the disorder as familial Mediterranean fever falls on a spectrum of various presentations; the recurrent episodes of familial Mediterranean fever may be so severe that the q...

Challenging case of Familial Mediterranean Fever and its management

Background Familial Mediterranean Fever (FMF) is an autosomal recessive disease which is characterized by recurrent, selflimiting, short attacks of serositis (peritonitis, pleuritis or arthritis), fever and erysipelas-like skin lesions along with a marked increase in acute phase reactants. Although FMF is not associated with immune-mediated tissue damage, however these individuals are prone to ...

Thoracic and lung involvement in familial Mediterranean fever (FMF).

Lung involvement in FMF is limited mainly to transient pleuritis during acute attacks. Amyloidosis of the lung is rare and is associated with symptomatic involvement of other organs while remaining subclinical in itself. Vasculitis of the lung in FMF is possible because of the strong association between FMF and a variety of vasculitides. With the exception of one case of isolated pulmonary vasc...

Protracted synovitis without systemic manifestations in familial Mediterranean fever (FMF).

Sirs, It is now being recognised that familial Mediterranean fever (FMF) also occurs in non-Mediterranean populations, including Japanese (1). The arthritis of FMF consists of acute attacks of pain and swelling of one articulation at a time, most frequently affecting the large joints of the lower extremities within 2-3 days duration (2). In some cases, however, protracted arthritis develops, mo...

How long is the diagnosis of Familial Mediterranean Fever (FMF) delayed in a region where FMF is common in Turkey?

Background and question Similar to other autoinflammatory diseases, diagnosis of FMF is often missed and markedly delayed, particularly when its prevalance is very low in a community. It’s reported that diagnosis of FMF might be delayed more than 20 years. Although Turkey is one of the countries with a high prevalence of FMF, the diagnosis of the disease is markedly delayed in clinical practice...