Evaluating the Frequency of Human T-Lymphotropic Virus Type 1 Infection in Iranian Population

Authors

  • Mahsa Najafzadeh Birjand University of medical sciences, Birjand, Iran
  • Mohammad Reza Ameli Blood Transfusion Research Center, South Khorasan Regional Transfusion Center, Birjand, Iran
  • Shirin Ferdowsi 1. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine,
Abstract:

Background: Human T-cell lymphotropic viruses 1 (HTLV1) is endemic in specific regions. We aimed to determine the prevalence of HTLV I infection among blood donors in southeast Iran.   Methods: This cross-sectional study was conducted between April 2005 and March 2015. Sera were collected from blood donors and were tested for the presence of HTLV1 specific antibody using ELISA. Reactive samples were then tested by Western blot for confirmation. Results: Of the 165,267 blood donors tested for HTLV 1 antibody, 45 (0.027%) donors were positive. Out of 45 positive donors, 41 were first time blood donors, 3 were repeat blood donors and 1 as regular donor. Most HTLV-1-positive donors were male and married. Co-infection with HBV was observed in one subject. The percentage of positive samples had increasing patterns from 0.016% in 2009 to 0.084% in 2010 and decreased after that to 0.014% in 2015. Conclusion: The results indicated a low level of infection of HTLV1 in this part of our country. 

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Journal title

volume 11  issue 2

pages  47- 50

publication date 2019-06

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