Epigenetics in diagnosis of colorectal cancer

Authors

  • Aga Sameer Basic Medical Sciences Department, College of Medicine- Jeddah, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, 21423. Kingdom of Saudi Arabia.
  • Saniya Nissar Department of Biochemistry, Kashmir University, Hazratbal, Srinagar, Kashmir, INDIA. 190006.
Abstract:

Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the early diagnosis of CRC. This will serve as the boon to the clinical management of the disease.

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Journal title

volume 5  issue 1

pages  49- 57

publication date 2016-02-01

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