Efficacy and Safety of Aripiprazole for Treatment of Irritability in Children with Autistic Disorder: An Open-Label Study
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efficacy and safety of aripiprazole for treatment of irritability in children with autistic disorder: an open-label study
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full textEmerging role of aripiprazole for treatment of irritability associated with autistic disorder in children and adolescents
Autistic disorder is a largely misunderstood and difficult to treat neurodevelopmental disorder. Three core domains of functioning are affected by autistic disorder, ie, socialization, communication, and behavior. Signs of autistic disorder may be present early, but are frequently overlooked, resulting in a delay in its diagnosis and a subsequent delay in treatment. No one definitive therapy is...
full textAripiprazole in the treatment of irritability in children and adolescents with autistic disorder.
OBJECTIVE The objective of this study was to evaluate short-term efficacy and safety of aripiprazole in the treatment of irritability in children and adolescents with autistic disorder who were manifesting behaviors such as tantrums, aggression, self-injurious behavior, or a combination of these. METHODS This 8-week, double-blind, randomized, placebo-controlled, parallel-group study was condu...
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Journal title
volume 40 issue 6
pages 548- 549
publication date 2015-11-01
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