Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments

Authors

Afsaneh Tavakoli Innovative Medical Research Center, Department of pharmacology, Mashhad Branch, Islamic Azad University, Mashhad, Iran

Majid Mirsadraee Department of Internal medicine, Faculty of Medicine, Islamic Azad University-Mashhad Branch, Mashhad, Iran

Shadi Ghafari Biologist, Shahid Hasehemi Nezhad Research center, Kavosh high school, Ministry of Education, Mashhad, Iran

Vahideh Ghorani Neurogenic Inflammation Research Centre and Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract:

Objective: The present study aimed to determine the effects of Rosmarinus officinalis (R. officinalis) and Platanus orientalis(P. orientalis) extracts on asthma. Materials and Methods: We conducted a randomized, double-blind, active-comparator study to evaluate the effect of P. orientalis and R. officinalis extracts on asthmatic patients resistant to routine treatment.The subjects were randomly divided into three groups receiving P. orientalis and R. officinalis extracts alone or in combination. The primary endpoints were clinical findings, spirometry, exhaled nitric oxide (FENO) and Asthma Control Test (ACT) assessed over the one-month treatment period. Results: ACT score showed significant improvement after treatment with R. officinalis (p

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Journal title

Avicenna Journal of Phytomedicine

volume 8 issue 5

pages 399- 407

publication date 2018-09-01

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Keywords

Asthma R. officinalis P. orientalis Sycamore Rosmarinic acid

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